There are many potential side-effects to taking statins. Potential Side-Effects of Statins. Some medications and supplements, such as birth control pills or niacin, can interfere with the effectiveness of cholesterol medications and increase the risk of side effects. So again, ask your doctor or your pharmacist, if you're on a statin, about any new drugs that you're put on to make sure that it's a safe combination. Definition of Moderate Drinking. Next: I Have Been Taking One Of The Statins. As such, refraining from alcohol consumption when taking pharmaceutical medication of any kind is, generally speaking, the best idea. Statin drugs work in the liver, which means it is important to use caution with alcohol while taking these drugs. To understand why any amount of alcohol could be a problem with Lipitor or any statins, ... there is likely much more to be concerned about than the effect on your liver of combining statins and alcohol. He works very long hours in the car sale industry and enjoys a day off and having a glass or two of wine, sometimes a vodka with 7-UP. I have noticed lately that his personality has changed. How to take statins safely If you're taking statins, be sure to let your doctor know about any other medications or over-the-counter supplements you're using. Alcohol and cholesterol medications known as statins: you may consider moderating your alcohol intake because statins mixed with alcohol may elevate triglyceride levels and possibly lead to liver damage. The following are some of the reports I have received from readers of my books and website articles regarding alcohol use along with statin drugs. The Food and Drug Administration lists liver damage as one of the potential dangers of taking statins, but this type of liver injury is considered rare. Statins may very rarely be associated with a type of lung disease. 1) My husband has been on Lipitor for about 5-6 years. 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