Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine. Tell your doctor right away if you develop any of these symptoms during treatment and if these symptoms last after your doctor stops this drug: muscle pain/tenderness/weakness (especially with fever or unusual tiredness), signs of kidney problems (such as change in the amount of urine). Do not double the dose to catch up. Do not take any red yeast rice products while you are taking ezetimibe/simvastatin because some red yeast rice products may also contain a statin called lovastatin. Ezetimibe is used to treat high cholesterol. https://www.webmd.com/drugs/2/drug-91437/ezetimibe-simvastatin-oral/details Brand Name: Zetia. US residents can call their local poison control center at 1-800-222-1222. This condition may be more likely to occur in older adults and in people who have kidney disease or poorly controlled hypothyroidism (underactive thyroid). Ezetimibe is a medication used to treat high blood cholesterol and certain other lipid abnormalities. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Talk with your doctor for details. Sign Up to Receive Our Free Coroanvirus Newsletter, How High Cholesterol Can Hurt Your Vision, homozygous inherited high blood cholesterol, heterozygous inherited high blood cholesterol. Do not share this medication with others. This medication must not be used during pregnancy. Do not take any red yeast rice products while you are taking ezetimibe/atorvastatin because some red yeast rice products may also contain a statin called lovastatin. Consult your doctor before breast-feeding. Do not take extra medicine to make up the missed dose. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Do not increase your dose or take this medication more often than prescribed. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. The information is not intended to cover all possible uses, directions, precautions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for you or anyone else. However, many doctors prescribe ezetimibe alone and combine it with a low-fat diet to help reduce cholesterol. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use ezetimibe only for the indication prescribed. What conditions does Ezetimibe-Simvastatin Tablet treat? Before taking this product, tell your doctor or pharmacist if you are allergic to ezetimibe or simvastatin; or if you have any other allergies. Are you considering switching to Ezetimibe-Simvastatin Tablet? Therefore, it is important to prevent pregnancy while taking this medication. Consult your doctor or pharmacist for more details. However, promptly talk with him or her about the risks and benefits of your higher dose. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Consult your pharmacist or local waste disposal company for more details about how to safely discard your product.Information last revised May 2020. If you take ezetimibe with another cholesterol medicine, follow your doctor's dosing instructions very carefully. This medicine will not be as effective in lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Until then, ezetimibe taken in addition to a statin may be a very good option. In combination with low-to-moderate statin dose treatment, or with second- or thirdline statins, ezetimibe is used in situations of statin-associated muscle symptoms. Canada residents can call a provincial poison control center. Grapefruit can increase the amount of this medication in your bloodstream. Non-statin options include ezetimibe, which limits the absorption of cholesterol, and a new group of drugs called proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors. You should not use ezetimibe with a "statin" cholesterol medicine if you have active liver disease, or if you are pregnant or breast-feeding a baby. Get emergency medical help if you have signs of an allergic reaction to ezetimibe: hives; difficult breathing; swelling of your face, lips, tongue, or throat. It is the first of a new class of cholesterol-lowering medications. Statins lower cholesterol by preventing the liver from synthesizing new cholesterol, while Zetia lowers cholesterol by preventing the intestine from absorbing cholesterol … You may need frequent blood tests to check your liver function if you take ezetimibe with a statin medicine. Consult your doctor for more details and to discuss the use of reliable forms of birth control (such as condoms, birth control pills) while taking this medication. It’s available as a generic drug and as the brand-name drug Zetia. Side effects may be more likely in older adults. Weaker yes statin no: Zetia (ezetimibe) is weaker than most statin medications when it comes to cholesterol reduction. Talk to your doctor about the benefits and risks. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. It is not known whether ezetimibe alone passes into breast milk or if it could harm a nursing baby. Praluent, Livalo, Zetia, atorvastatin, simvastatin, rosuvastatin, Lipitor, Crestor. Ask your doctor or pharmacist for more information. Take this medication by mouth with or without food as directed by your doctor, usually once daily in the evening. How does Zetia work to lower cholesterol? This list is not complete. Copyright(c) 2020 First Databank, Inc. Are you taking Ezetimibe-Simvastatin Tablet? Common ezetimibe side effects may include: This is not a complete list of side effects and others may occur. How long have you been taking Ezetimibe-Simvastatin Tablet? The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Zetia is the brand name for the drug ezetimibe. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. This medication may rarely cause liver problems. 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